Stem cells could be used to restore the brain cells whose death causes Parkinson’s disease, says scientist at the Karolinska Institute in Sweden. Parkinson’s disease results in slow movement and involuntary shaking of the body parts. This is due to deficiency of dopamine, a chemical that gives messages to the brain.
The experiment was carried out on mice and humans. Four genes were mixed with certain molecules that were reprogrammed and seen under a microscope. It was observed that human neurons were grown in a dish and similarly happened with brain cells of mice. “The new thing in this study is that they used programming to convert an astrocyte into a neuron that is functional in people”, said Ernest Arenas, the lead researcher. “It’s the absolute very first prototype of this type of strategy and we are unaware of the problems that we might face while developing a cure in future. The focus was on demonstrating it’s possible”, he added.
There is no treatment for Parkinson’s disease as it is neurodegenerative that has affected 10 million people along with famous actor Michael J. Fox. Instead of replacing the missing dopamine scientist have tried to replace the entire dopamine neurons. Scientists are trying this experiment since the late 1980s. In their first approach, scientists obtained dopamine neurons from the first-trimester aborted fetuses and implanted into the patients’ brain. This experiment caused a serious dyskinesia in about 20 percent of the patients, Beck said.
The Karolinska lab is making the morphed cell technique safer and effective by generating the viruses that give out reprogramming molecules only to astrocytes. “We are exposed to collaborations” aimed at human studies, Arenas said.
“This study is a future work of research showing that mouse astrocytes could be converted into dopamine neurons. Now we have put a step forward and planned to move the cells form mouse to human”, said Patrick Lewis, an associate professor of cellular and molecular neuroscience at the University of Reading.
Daniel is acting editor of Talk Herald with over two years of experience in the field of online news under his belt. Daniel has worked with multiple media houses and is currently leading a team of journalists, sub-editors, and writers through his entrepreneurial endeavors.
Your email address will not be published. Required fields are marked *
United StatesCanadaMexicoUnited Kingdom-----AfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntigua and BarbudaArgentinaArmeniaArmeniaArubaAustraliaAustriaAzerbaijanAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBonaireBosnia and HerzegovinaBotswanaBouvet Island (Bouvetoya)BrazilBritish Indian Ocean Territory (Chagos Archipelago)British Virgin IslandsBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongoCook IslandsCosta RicaCote d'IvoireCroatiaCubaCuraçaoCyprusCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuamGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and McDonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIranIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKazakhstanKenyaKiribatiKoreaKoreaKuwaitKyrgyz RepublicLao People's Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedoniaMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMartiniqueMauritaniaMauritiusMayotteMicronesiaMoldovaMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNetherlands AntillesNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorthern Mariana IslandsNorwayOmanPakistanPalauPalestinian TerritoryPanamaPapua New GuineaParaguayPeruPhilippinesPitcairn IslandsPolandPortugalPuerto RicoQatarReunionRomaniaRussian FederationRwandaSaint BarthelemySaint HelenaSaint Kitts and NevisSaint LuciaSaint MartinSaint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Netherlands)Slovakia (Slovak Republic)SloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia & S. Sandwich IslandsSpainSri LankaSudanSurinameSvalbard & Jan Mayen IslandsSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzaniaThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkeyTurkmenistanTurks and Caicos IslandsTuvaluU.S. Virgin IslandsU.S. Minor Outlying IslandsUgandaUkraineUnited Arab EmiratesUruguayUzbekistanVanuatuVenezuelaVietnamWallis and FutunaWestern SaharaYemenZambiaZimbabwe
Knife Gate Valves Market Globally 2018 : Flowrox, Orbinox, VAG and WEY Valve
Global Herbal Medicine Market Size 2018: Arkopharma, Schwabe, Tsumura, Madaus, Blackmores and Weleda
Global Ice Hockey Helmet Market Forecast 2018-2023: Eagle hockey, Warrior Sports, Grays and Graf
Global 3D Metrology System Market Growth(CAGR) by 2022: Nikon, Keyence, Mitutoyo and FARO
Global Cervical Dilator Market Size 2018: Sklar Instruments, Purple Surgical, Cook Medical and Medgyn
Global Portable Hard Disk Drive Market Size 2018: Seagate, Toshiba, Hitachi, Fujitsu and Western Digital
Global Water Filtration Systems Market Size, Share 2018: Toray, Midea, Honerwell and Watts
Global Intravascular Ultrasound Devices Market Size, Share 2018: InfraReDx, Terumo Corp and Philips Healthcare
North America Plastic Bandages Forecast Market 2018-2023: Medline Industries, Acelity, Smith & Nephew, Medtronic and Yunnan Baiyao
Global Rotary Pressure Filters Market Forecast 2018-2023: BHS, Juneng Machinery Group, Gneuss, ANDRITZ and BOKELA
Global DeNOx Catalyst Market Growth(CAGR) by 2022: Johnson Matthey, Seshin Electronics, Haldor Topsoe and Hitachi Zosen
Sprocket Market Globally 2018 : Linn Gear, SKF, G&G Manufacturing, Katayama, Renqiu Chuangyi and Renold
Global Wheel Weight Market Forecast 2018-2023: Baolong, Holman, Jiangyin Yinxinde, 3M and Trax JH Ltd
Global Sulfolane Market Forecast 2018-2023: New Japan Chemical(JP), CASIL Industries(IN) and Sumitomo Seika Chemical(JP)
Global Healthcare BPO Market Size, Share 2018: Parexel, Inventiv, Lonza and Catalent
Global Wind Power Casting Market Growth(CAGR) by 2022: Graco, Marpac, Conair, Cloud B and HoMedics
Global Butyl Rubber Market Forecast 2018-2023: PJSC NizhneKamskneftekhim, Lanxess, Sibur, JSR and ExxonMobil
Global Agate Market Size 2018: Hongshanyu, Kingda Ceramic, Ravenil SA and Antolini
Global Machine Screws Market Forecast 2018-2023: Monroe, Foreverbolt and Tong Ming
Global Cycloidal Gear Reducers Market Size 2018: Fixedstar, Rotork plc, ONVIO, Varitron and CDS Corporation
Global High Power Lasers Market Size 2018: Coherent, Rofin, TRUMPF, nLIGHT and IPG Photonics
Global Sofa Market Forecast 2018-2023: LES JARDINS, Varaschin spa, Hkroyal and Quanyou
Asia-Pacific Plywood Forecast Market 2018-2023: Xingang, Penghong, Shengyang, Happy Group and DeHua
Global Cell Culture Media Market Size 2018: CellGenix, Atlanta Biologicals, PromoCell, Takara and Zenbio
Global Chondroitin Sulfate Market Forecast 2018-2023: Nippon Zoki, GGI, Huiwen, Summit Nutritionals and Sioux Pharm
COPYRIGHT - 2017 JOURNALISM DAY